Fig. 2
From: Biomarker discovery with quantum neural networks: a case-study in CTLA4-activation pathways
A Activation Pathways Analyzed in Our Case-study: We expanded the scope of immunological research by studying the coactivation of CTLA4, CD2, and associated genes, including CD48, CD53, CD58, and CD84. These molecules play significant roles in T-cell immune regulation, and their interactions could potentially lead to the development of more effective therapeutic strategies for various immune-related diseases. B Venn Diagram of Discovered-Genetic Biomarker Sets regarding The Quantified Targeted Pathways: MACF1, a protein facilitating actin-microtubule interactions at the cell periphery, is a common genetic biomarker for both CTLA4 and CTLA4-CD8A-CD8B pathways. On the other hand, HSPA1B, a member of the heat shock protein 70 family that stabilizes existing proteins against aggregation, is the common genetic biomarker for CTLA4-CD8A-CD8B and CTLA4-CD2 pathways. These findings highlight the potential of these biomarkers in understanding immune regulation and developing therapeutic strategies, which has not yet been well-studied, discussed in "CTLA4-activation Pathways" section